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0B7-33 (5mg)
0B7-33 (5mg)

0B7-33 (5mg)

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$95.00

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MADE IN USA

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

What is 0B7-33?

0B7-33 is a synthetic peptide analog derived from the C-terminal region of B-type natriuretic peptide (BNP). This peptide has been studied for its potential role in preventing and reversing cardiac fibrosis, particularly in models of heart failure. By selectively targeting the natriuretic peptide clearance receptor (NPR-C), 0B7-33 avoids vasodilatory side effects while maintaining anti-fibrotic efficacy. It represents a promising direction in cardioprotective and anti-remodeling therapies.

Chemical Structure of 0B7-33

A fragment of BNP, 0B7-33 consists of a truncated sequence that retains affinity for NPR-C while eliminating natriuretic and hypotensive properties. Specific sequence data is proprietary in most literature.

What Are the Effects of 0B7-33?

Anti-Fibrotic Activity

Research indicates 0B7-33 can reduce myocardial fibrosis by decreasing fibroblast proliferation and extracellular matrix deposition. This may preserve cardiac function in heart failure or hypertensive damage.

Cardiac Remodeling Prevention

0B7-33 may inhibit pathways involved in maladaptive remodeling of the heart, potentially slowing disease progression.

Organ Protection

Studies show it may also offer protective effects to other organs vulnerable to fibrotic conditions, including kidneys and liver.

Selective Action

By targeting NPR-C specifically, 0B7-33 offers anti-fibrotic action without vasodilation, making it safer in certain clinical settings.

COA

Certificate of Analysis

*Issued under Paramount Peptides, the authorized testing and distribution partner.

HPLC

High Performance Liquid Chromatography

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